The persistent fever is gone and we've never found out what really caused it in the first place. But who really cares at this point when...
It's almost a week since surgery and Alexander is doing very well. As
Dr Bruce promised, the swelling would start going down just about as
quickly as it came up after Alexander's surgery.
The past week has been a miracle unto itself. Alexander progressed very
quickly after surgery and went through a couple of PICU step-downs until
he hit the general neurology floor not very long after his surgery.
That's pretty amazing considering that only a day or two before, his
brain was being operated upon! The advances in medical technology are
just plain amazing.
Dr Bruce was pleased enough with his progress that he returned home to
Nantucket on Friday. He has a flat not too far from Children's for when
he does surgery in Washington but his home is on the island. A word
about that...he stayed an extra week in Washington for the purpose of
doing Alexander's surgery. If that doesn't tell you what kind of a
stand-up guy he is, I don't know what will.
We've been awfully pleased with the results of the surgery as well. In
the past week, Alexander has been far more alert and awake than he had
been for his entire life before the surgery. Come what may, that was
one of what has been many miracles since his surgery.
I think it's safe to say that Dr Bruce and his team have given us our
son back to us with a much better prognosis and quality of life than
what he had before the surgery. That's not to say that there aren't
potential problems down the road but for what we wanted to do (stop the
seizures), it appears to have been done. The fact that he's quite alert
and half of the seizure medicines have already been discontinued and the
phenobarb is being ratcheted down is a very good development.
With that in mind, we were making preparations to get under way today...
to the point of singling up all of the lines and turning the screws for
a quick cruise in a southwesterly direction.
That is, until Alexander started running a fever!
Having been through one U-turn to the hospital, we weren't all that keen
to do another one. So whilst we get to stay here for them to try to find
out what was causing the fevers, Grammy and Nicholas hitched a ride with
Gramps for the trip back to North Carolina. At least some of us are
going home.
But don't worry guys, we'll be on the road behind you before you know it.
We went by the hospital at o' Dark Thirty to see our little guy
and he's recovering from the surgery just fine. He still had the breathing
tube installed but he was definitely more alert and it's not long before
that tube is gone. Then he gets Pedialyte and if that stays where
it needs to, then he gets back to feeding on breast milk as soon as
possible. He may be booted from PICU as early as tonight or it may
happen tomorrow.
There is definitely a lot of swelling on the right side and toward the
back of his head but the swelling that was evident in his face last
night had actually improved. We're told this is because Mommy ordered
Alexander to do a fair bit of peeing and it seems that he's been taking
her orders seriously. :)
Every now and then, he would try to cry but would just turn beet red
instead. But that's not necessarily a bad thing!
We caught Dr Bruce after his rounds and he was still very pleased with
how things were progressing for Alexander which was very reassuring. He
figures that tube is coming out quicker with Alexander getting more alert
and grabbing onto it.
Beware the ides of March! That's good advice if you're a Roman Emperor
or an area of cortical dysplasia because there are sharp things coming
right at you to take you out!
Of course, things always work smoothly and on-time in our nation's
capital, right? Anyone who has flown into Reagan National (DCA) or
Dulles (IAD) can tell you, the airspace round the capital is congested
and getting racked, packed, and stacked is a fact of life. Well, you've
just described the holding pattern circling above Children's operating
suites as well.
So when I arrived on scene half an hour before surgery was due to start
(1100 hours), we found out that surprise, surprise...the pattern
was completely full and we'd have to circle a bit before landing. But
that's OK...that gave Mommy a chance to catch a much-needed cat nap and
me to hold him for quite a while.
Of course, Alexander hadn't really had anything to eat since 0230 this
morning (apparently surgery and a full stomach don't mix!) so you can
just imagine how much he was loving the delay. Yeah...right
unhappy and that pacifier just wasn't pacifying our little boy.
After circling for about an hour and a half, he was cleared for landing
to the operating suite down one floor and it took us twenty minutes to
navigate the rabbit warren that is this (or any other, for that matter)
hospital. Initially, there was a bit of confusion as to where he was
going but we did manage to get to a holding room where we could hold and
kiss him one more time before it was his time to star in his own special
episode of ER.
Time on the clock: 12:20 PM.
After Alexander went off with the gas passers (ha ha!), we had a decision
to make as far as making some of the removed tissue available to a
researcher at Harvard who is trying to discover why the neurons get
stopped in their migration to the outer part of the brain and then back
in again. Because Alexander is a unique case, his tissue may be of
particular interest in this research and who knows, he might well help
other little ones who have his same condition.
Time on the clock: 14:32 PM.
The IV lines have been placed:
We met with Dr Bruce today to read the runes (MRIs) of the area and
hear the proposed surgical solution. This was my first time meeting
Dr Bruce and he's definitely as genial and nice as has been advertised.
Plus he's got a fanstastic wit thoroughly in keeping with his Scottish
heritage (from Edinburgh).
The reading was consistent with the cortical dysplasia theories that we
had been getting from other facilities. What makes Alexander relatively
unique is that it's apparently unusual to see a focal dysplasia covering
a relatively large area. Typically, focal dysplasias tend to be very
small and the non-focal ones usually result in the whole hemisphere
being removed.
As it was explained to us, the neurons in the brain migrate outward from
the center and then back again to form the pathways. This particular
region where the dysplasia is had something interrupt that migration and
the neurons are just disorganized. Because of that disorganization, the
signals coming from that region are not normal and thus leading to the
seizures.
It has been obvious by now that the witches brew of medications has been
unsucessful in controlling the seizures and that surgery to remove that
area of the brain is required. It does him no good for the disorganized
neurons to stay in there because of the bad signals so it's got to come
out and the quicker, the better.
There is a 70-80% chance that removing the dysplasia will stop the
seizures cold. There might be a few 24-48 hours after surgery because
of irritation to the brain and they might be different in character
(more tonic-colonic) but afterwards should go to nil provided all of the
affected area has been removed. The area in question will fill with
spinal fluid and there isn't any expectation of deficits in relocatable
services/pathways.
The concern is the proximity of the dysplasia to the motor pathway and
because the dysplasia is on the right side, the left side would be
affected. Unfortunately, it's hard to say what the ultimate effects
would be...it could be undetectable to weakness and no fine motor
skills in the left hand (the hand is more likely than seeing the leg
affected) making that hand useless. We won't know that for some months
to come.
The hope is that Dr Bruce will get all of the dysplasia out in the first
surgery. There are other areas that might need attention further down
the road which might require follow-on surgery but the big deal is to
get the known area taken care of first making it easier to fix other
areas later on.
Of course, any time you've got surgery, you've got risks up to and
including death but we've been assured that because there appears to be
nothing else wrong with Alexander, these possibilities are remote but
cannot in good conscience be reduced to nil.
Thus, we're at the point probably every parent in the world dreads...
having to sign the consent for surgery. When you've got the best in the
world doing the operating, that's pretty much a no brainer (Dr Bruce at
this point shows his wit indicating that if we want the operation, we've
got to sign the thing...apparently a bit different way of putting it
than Julia is used to but certainly on the mark nonetheless).
The first hour in the surgery will be used to put him under the influence
of anaesthesia and take the opportunity to insert a more permanent
intravenous (IV) placing. This will allow IV fluids to be given without
having to continually stick him. After seven weeks, six of which have
been in three hospital facilities...Alexander's veins (and Alexander!)
have been poked and prodded enough that he's doing a good representation
of a pin-cushion.
The actual surgery itself is expected to take three or four hours but
we've been ordered not to freak out if it goes a bit longer. As far as
we're concerned, take your time and do it right. The old measure
twice, cut once rule is just as important in surgery as it is in
carpentry!
Once out of surgery, Alexander heads straightaway to intensive care
(PICU) where he'll spend the next couple of days to recover from the
surgery. He will have quite noticeable swelling on the right side down
to his right eye but that should subside. He's then expected to get
back to feeding and will be stepped down appropriately as his condition
improves. With any luck, the seizures will be gone and he will go home
with much less medications than he's been getting (and we get a more
alert baby, happy bonus!).
That means we've probably got another week up here and a follow-up
trip six weeks after he comes home along with scans for the next couple
of years (but that can be done in Raleigh).
If that's the price we've got to pay to have our son have as best a
quality of life as we can give him, we will gladly pay it.
BTW, Alexander passed the ten pound mark today!
Alexander is being transferred from Duke to Children's National
Medical Centre in Washington, D.C. after having a consultation from
Dr Derek Bruce. The signs were pointing to surgery and of course, any
time you want to operate on our kids (or anyone we care about), if time
allows, we're going for that second opinion!
We had contacted one of the doctors that works with Julia to see if she
had any ideas on getting that second opinion from a neurosurgeon. After
she had worked the phones for three days, we were put in contact with
Dr Bruce.
He personally called her back (a highly regarded neurosurgeon, possibly
the best in the world!) which in and of itself is regarded as unusual.
But then even better, he spent thirty minutes with her discussing the
case and after she was done, it was as if a load had been lifted from
her shoulders and she could see a concrete plan to try to solve Alexander's
problem with the seizures. A bit of Google action revealed that Dr Bruce's
CV is as impressive as his bedside manner and we had no problems feeling
comfortable with working a transfer to Children's in Washington, DC.
Dr George at Duke eventually came round and confirmed the diagnosis of
focal cortical dysplasia and indicated that he could perform the surgery
in the coming week. But at that point, the decision was taken to go
ahead and go see Dr Bruce. I'm sure that Dr George would do a good job
but when you have a chance at getting the pediatric neurosurgical
equivalent of Wayne Gretzky performing the operation, that's really
a no-brainer.
It's also a no-brainer when the past couple of weeks have basically
been a case of playing with his medications and doing more MRIs for the
most part. So bye-bye Duke, hello Washington!
So today, Alexander and Mommy got to ride a Super King Air 200 from
Raleigh-Durham International Airport (RDU) to Dulles International (IAD)
and were then transported by ambulance directly to Children's in
(technically) northwest DC (DC is laid out in quadrants centered on the
Capitol building...Children's is directly north of the Capitol and just
barely west of North Capital Avenue).
Med Center Air
Grammy, Nicholas, and Daddy got the less impressive ground route from
Zebulon to Washington, DC...including remembering just how much Beltway
traffic stinks normally but particularly on a Friday night with
less-than-stellar weather conditions. We had passed through storms in
Richmond and the expectation was for a snow storm in Washington (which
fortunately never came to pass!). It took about four and a half hours
to get to the Washington area (with a stop north of Richmond for dinner
and fuel) and then another 90 minutes to get round the western part of
the Beltway to get to Children's using Georgia Avenue. Of course, we
might have saved some time if the streets were better lit and signed
but we got a good tour of Howard University, nonetheless. We even
passed Walter Reed Army Hospital once. But we eventually found our way
round to Children's National Medical Centre.
We're staying at the Ronald McDonald House about two miles to the
northeast of the hospital and it looks to be a wonderful place. It's
certainly a lot more affordable than the hotels round here. And the
parking is cheaper, too.